解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Gynecological literature is replete with multiple papers on sexually transmitted infections (STIs) in young women. Although those past the reproductive prime may well be at lower risk for STIs than women in the peak reproductive years, STIs are regularly seen in the older cohort and are a cause for significant morbidi...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2010.05.003
更新日期:2010-10-01 00:00:00
abstract:INTRODUCTION:Endometriosis is a common disease in women of reproductive age. The symptoms usually disappear after a natural or a surgical menopause. Estrogen-based hormone therapy is required in women with premature or early menopause until the average age of the natural menopause and should be considered in older wome...
journal_title:Maturitas
pub_type: 共识发展会议,杂志文章,实务指引
doi:10.1016/j.maturitas.2010.04.018
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVES:Menopausal status is a common covariate in epidemiologic studies. Still, there are no standard definitions for menopausal status using observational data. This study assesses distinctions between menopausal status definitions using commonly collected epidemiologic data, and explores their impact on study out...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2010.04.015
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVES:The purpose of this review is to summarize the effectiveness of select vitamins, minerals and trace elements in postmenopausal women for their effects on bone health, cardiovascular health, breast cancer, cognition and vasomotor symptoms. METHODS:Review of the relevant literature and results from recent cli...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2010.06.003
更新日期:2010-08-01 00:00:00
abstract::It is widely recognised that women's sexuality can be particularly complex after breast cancer, with sexual changes often becoming the most problematic aspect of a woman's life. The impact of such changes can last for many years after successful treatment, and can be associated with serious physical and emotional side...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2010.03.027
更新日期:2010-08-01 00:00:00
abstract::Almost without exception clinical research seeking to evaluate the effectiveness of Chinese medicine relies on TCM textbook knowledge - accessed directly or via practitioners' clinical usage - in order to frame its hypotheses. Recent historical research shows that these textbooks, products of a politically directed pr...
journal_title:Maturitas
pub_type: 历史文章,杂志文章
doi:10.1016/j.maturitas.2010.03.021
更新日期:2010-08-01 00:00:00
abstract:INTRODUCTION:Epilepsy is a major public health problem worldwide which is clinically characterized by recurrent seizures. AIM:The aim of this position statement is to provide evidence-based advice on management of the menopause in postmenopausal women derived from the limited data available. MATERIALS AND METHODS:Lit...
journal_title:Maturitas
pub_type: 共识发展会议,杂志文章,评审
doi:10.1016/j.maturitas.2010.03.026
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVES:Studies focusing on lifestyle and health factors and stress urinary incontinence (SUI) are scarce in Japan. The aim of this study is to examine the association of lifestyle and health factors in SUI. METHODS:Study subjects were retrieved from Japanese women participating in a health checkup program provided...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2010.04.002
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:Physical and psychological incapacity, including fear of falling is related to decreased satisfaction with life in osteoporosis (OP). The impact of a balance exercise program on improving the quality of life is not well established. We have, therefore, investigated the effect of 12-month Balance Training Prog...
journal_title:Maturitas
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.maturitas.2010.03.009
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Several studies drawn from the Ecuadorian population have previously reported that more than half of mid-aged women present hot flushes, which can impair their quality of life. However up-to-date risk factors for their presence and severity have not been assessed. OBJECTIVE:To assess hot flush frequency and...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2009.11.024
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:To evaluate whether prolonged physical activity (25 km/week running for 8 years) modifies GH decline. DESIGN:The GH response to maximal exercise on bicycle-ergometer was tested in younger (26-30 years) and older (42-46 years) healthy women. Each age group included 2 subgroups of 10 sedentary and 10 runners, ...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2009.12.020
更新日期:2010-04-01 00:00:00
abstract::Heart disease is a major cause of death, disease and disability in the developed world for both men and women. Women appear to be under-diagnosed and treated both because they fail to visit the doctor or hospital with relevant symptoms and because doctors tend to dismiss the seriousness of women's symptoms of heart di...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2009.11.019
更新日期:2010-03-01 00:00:00
abstract:CONTEXT AND OBJECTIVE:The aim of this study was to describe hot flushes in men with prostate cancer, and their treatment methods. METHOD:A systematic review was conducted of the literature indexed between 1966 and 2009 on the MEDLINE, the ISI Web of Knowledge, Cinahl and PsycINFO. Of 252 articles identified, 32 were s...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2009.10.017
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:There is an assumption in menopause research that attitudes to menopause are influenced by a range of cultural, social and psychological variables, which may in turn affect menopausal experience and symptom reporting. However, many studies draw conclusions about this relationship without explicitly examining...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2009.10.016
更新日期:2010-01-01 00:00:00
abstract::Associations between depression and impaired functioning are well known and have been documented in numerous clinical, primary care and epidemiological studies. Reviews of this research have focused on the elderly. Recent studies suggest that women become increasingly vulnerable during the menopausal transition to dec...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2009.09.017
更新日期:2009-11-20 00:00:00
abstract::Administration of calcitonin gene-related peptide (CGRP) or adrenomedullin (AM) can cause facial flushing, suggesting that the peptides may be important in hot flushes experienced particularly by post-menopausal women. Five studies have measured plasma CGRP concentrations in post-menopausal women who suffer from flush...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2009.08.011
更新日期:2009-10-20 00:00:00
abstract::Population health outcomes are shaped by complex interactions between individuals and the environments in which they live, work and play. Environments encompass streets and buildings (physical environment), attitudes, supports and relationships with others (social environment), as well as social and political systems ...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2009.07.011
更新日期:2009-09-20 00:00:00
abstract:OBJECTIVE:To correlate circulating hormone levels with the clinical and biological features of the tumors in menopausal breast cancer patients. DESIGN:Circulating hormone levels were measured in 161 previously untreated menopausal breast cancer patients within 72 h of their planned surgery. The obtained hormone levels...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2009.07.001
更新日期:2009-09-20 00:00:00
abstract:OBJECTIVE:The use of hormone replacement therapy (HRT) declined strongly in many countries after publication of the WHI-study. The purpose of the present study was to investigate HRT usage patterns and motives for initiation, temporary discontinuation, and permanent discontinuation of HRT use among Norwegian women. ME...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2009.07.010
更新日期:2009-09-20 00:00:00
abstract::Dementia has often thought to be unavoidable and incurable. In recent years, risk factors, including lifestyle attributes, have been associated with the two commonest forms of dementia, Alzheimer's Disease and vascular dementia. There is also new evidence that the adult brain maintains plasticity and response to exter...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2009.06.008
更新日期:2009-08-20 00:00:00
abstract::Most health decisions occur in contexts of scientific uncertainty, the "grey zone" of decision-making and many decisions faced by menopausal women are no exception. These contexts are characterized either by scientific evidence that points to a balance between harms and benefits within or between options, or by the ab...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2009.01.013
更新日期:2009-07-20 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate bone protective effects of risedronate, atorvastatin, raloxifene and clomiphene citrate in ovariectomized rats. METHODS:Our study was conducted on 63 rats at Experimental Research Center of Celal Bayar University. Six-month-old rats were divided into seven groups. The...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2009.03.018
更新日期:2009-07-20 00:00:00
abstract::At least 16 million women over the age of 50 currently experience low sexual desire, with approximately 4 million women exhibiting hypoactive sexual desire disorder (HSDD). Although early research established that testosterone therapy improves sexual desire in postmenopausal women, safer and more efficacious administr...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2009.04.008
更新日期:2009-07-20 00:00:00
abstract::In Western countries, cardiovascular disease is the leading cause of death in women. Prevalence of risk factors and clinical presentation are different in men and women and it is important to take these differences into account in both prevention and treatment. A healthy diet can substantially reduce cardiovascular ri...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2009.02.003
更新日期:2009-05-20 00:00:00
abstract::While the benefits of progestins in hormonal replacement therapy are well recognized as far as endometrial protection is concerned the data on breast tissue and the cardiovascular system are contentious. Following the Women's Health Initiative study, the Million Women Study and The Women's International Study of Long-...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2008.12.019
更新日期:2009-04-20 00:00:00
abstract::From a longitudinal prospective study, 160 women with spontaneous menopause and without steroid medication were followed during the transition from pre- to postmenopause. After 12 years 152 women were still participating in the study. Blood samples were drawn every 6 months until 1 year after the menopause and every 1...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2008.09.010
更新日期:2008-09-01 00:00:00
abstract::We designed a randomized double-blind randomized trial to examine the short and long-term effects of alternative approaches commonly used to manage menopause symptoms. Women were randomly assigned to: (1) black cohosh 160 mg daily; (2) multibotanical (50 mg black cohosh, alfalfa, chaste tree, dong quai, false unicorn,...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2008.11.014
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVES:To design a valid and reliable questionnaire, the Malaysian Osteoporosis Knowledge Tool (MOKT), to assess the knowledge of postmenopausal osteoporotic women in Malaysia, on osteoporosis and its treatment. METHODS:A 40-item instrument was designed and tested in this study. The scores ranged from 1 to 40, whi...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2008.04.006
更新日期:2008-06-20 00:00:00
abstract:OBJECTIVES:The purpose of this review is to focus on the importance of metabolic syndrome (MBS) and its increased prevalence in postmenopausal (PM) women. Also the role of hormonal therapy in PM women with MBS will be discussed. METHODS:Review of the relevant literature and results from recent clinical trials. RESULT...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2008.02.008
更新日期:2008-05-20 00:00:00
abstract:OBJECTIVE:In obese postmenopausal women with normal glucose metabolism (NGT) and impaired glucose tolerance (IGT) we assessed serum leptin, adiponectin, resistin, soluble leptin receptor (sOB-R) during oral glucose tolerance test (OGTT) in order to investigate their response to acute changes in glucose and insulin in t...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2008.03.012
更新日期:2008-04-20 00:00:00
abstract:OBJECTIVE:To investigate the potential impact of aromatase inhibitors, given after stopping tamoxifen treatment, on the endometrium of postmenopausal breast cancer patients. METHODS:Review of all available literature of studies on aromatase inhibitor therapy in postmenopausal breast cancer patients previously treated ...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2008.03.001
更新日期:2008-04-20 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the effects of tamoxifen on the weight and thickness of the urethral epithelium of castrated female rats. METHODS:Forty castrated adult female Wistar-Hannover rats were randomly divided into two groups: Group I (n=20) in which the animals received only the vehicle (prop...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2008.02.010
更新日期:2008-03-20 00:00:00
abstract:OBJECTIVE:Mandibular indices, measured on panoramic radiographs, may be useful screening implements for low skeletal bone mass density (BMD). Recent studies suggest that radiographic examination of mandible may constitute an effective process for the early diagnosis of osteoporosis. Biochemical markers of bone turnover...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2008.01.006
更新日期:2008-03-20 00:00:00
abstract:BACKGROUND:Increased frequency and severity of menopausal symptoms have been associated to black race. However, this situation has not been described in any Latin American population. OBJECTIVE:Compare frequency and severity of menopausal symptoms among Afro and non-Afro Hispanic Colombian climacteric women. METHODS:...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2007.12.002
更新日期:2008-02-20 00:00:00
abstract:OBJECTIVES:The aim of the present study was to evaluate the effects of low doses of hormone replacement therapy (HRT) in normal young postmenopausal women. METHODS:In an open trial healthy, non-obese postmenopausal women received for 2 years a low-dose continuous combined HRT (LD-HRT) containing 1mg estradiol+0.5 mg n...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2007.10.007
更新日期:2008-01-20 00:00:00
abstract:OBJECTIVE:The physiological role of parathormone (PTH) in the maintenance of bone mass in humans has not been fully defined. The main objective of the present study was to evaluate basal and EDTA-stimulated PTH levels in young women (Group Y=30.9 years, N=7) and in women in late menopause (Group M=64.7 years, N=7) and ...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2007.10.002
更新日期:2008-01-20 00:00:00
abstract:OBJECTIVE:To assess the risk of onset of menopausal symptoms at different periods surrounding menopause, and variations in this risk according to age at menopause and type of menopause. METHODS:We analyzed the 27,897 women participating in the French E3N cohort study who reached menopause during a 10-year follow-up pe...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2007.09.012
更新日期:2007-12-20 00:00:00
abstract:OBJECTIVES:Study to compare the effects of tibolone and raloxifene on health-related quality of life, sexuality and vaginal atrophy. METHODS:A double-blind, randomized study was conducted in 308 osteopenic, but otherwise healthy, postmenopausal women (mean age 66 years) who received tibolone 1.25mg/day or raloxifene 6...
journal_title:Maturitas
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.maturitas.2007.07.005
更新日期:2007-10-20 00:00:00
abstract::Vitamin D is a hormone that controls phosphorus, calcium, and bone metabolism and neuromuscular function. Vitamin D synthesis is a process in which the skin, liver, and kidney are sequentially involved. The vitamin D pool is completed by the amount taken with food and supplements. Vitamin D deficiency causes osteopeni...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2007.05.002
更新日期:2007-10-20 00:00:00
abstract:OBJECTIVES:We conducted this study to examine premenopausal risk factors associated with premature ovarian failure (POF) and early menopause (EM) among Korean women. METHODS:A 73% of total women aged 30-69 at four districts in the KMCC (Korean Multi-center Cancer Cohort) was participated in this study during 2002-2003...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2007.04.001
更新日期:2007-09-20 00:00:00